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Month-by-Month Expectations

What average weight loss actually looks like over the first year — from the pivotal trials, not from marketing.

STEP trials

Cumulative total body-weight loss

15.2%

average at month 12

Month 1

2%

Appetite change begins, initial dose settling.

Month 3

7%

Gating checkpoint — dose advance reviewed.

Month 6

12%

Steady loss, dose near target.

Month 12

15.2%

Approaching plateau, maintenance-focused.

These curves are population averages from published clinical trials (STEP for semaglutide, SURMOUNT for tirzepatide), not predictions for any individual. Your own trajectory depends on dose tolerance, protein intake, activity, sleep and underlying conditions. Educational only — not a prescription.

Next step

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